Semaglutide 10mg Peptide – Research Grade

Semaglutide is a long-acting glucagon-like peptide-1 (GLP-1) receptor agonist engineered for extended biological activity and enhanced metabolic stability. This synthetic peptide analogue contains structural modifications designed to increase albumin binding affinity and resistance to enzymatic degradation by dipeptidyl peptidase-4 (DPP-4), resulting in a prolonged half-life suitable for sustained receptor activation.

The Semaglutide 10mg peptide formulation is supplied as a lyophilized research compound intended for laboratory and investigational applications. Upon reconstitution, the peptide demonstrates high purity and molecular consistency appropriate for analytical, biochemical, and receptor-binding studies.

Technical Characteristics

• Molecular Formula: C187H291N45O59
• Molecular Weight: Approximately 4113.58 g/mol
• Sequence Type: Modified GLP-1 analogue
• Appearance: White to off-white lyophilized powder
• Solubility: Soluble in bacteriostatic water and compatible peptide solvents
• Purity: Typically ≥99% by HPLC
• Stability: Optimized for enhanced plasma stability and prolonged activity

Mechanism of Action

Semaglutide functions through selective activation of the GLP-1 receptor, a key regulator involved in glucose metabolism, insulin secretion, gastric emptying, and appetite signaling pathways. Activation of these receptors promotes glucose-dependent insulin release while suppressing glucagon secretion under hyperglycemic conditions. The peptide additionally influences central satiety pathways associated with caloric intake regulation.

Structural modifications within Semaglutide increase fatty acid-mediated albumin binding, significantly extending systemic circulation time compared to native GLP-1 peptides. These pharmacokinetic enhancements make it suitable for extended-duration metabolic and receptor interaction research.

Research Applications

Semaglutide 10mg peptide is commonly utilized in investigational settings involving:

• GLP-1 receptor pathway analysis
• Metabolic signaling studies
• Appetite and satiety mechanism research
• Endocrine and pancreatic function investigations
• Peptide stability and pharmacokinetic evaluations
• Obesity and glucose metabolism models

Storage & Handling

• Store refrigerated at 2–8°C before reconstitution
• Protect from direct light and excessive moisture
• For long-term preservation, storage at −20°C is recommended
• Reconstituted solutions should be handled using sterile laboratory procedures

Important Notice

This product is intended strictly for laboratory research, analytical, and investigational purposes only. It is not intended for human consumption, medical use, or diagnostic applications. Handling should be performed by qualified professionals in appropriately equipped research environments.